品牌 |
Leading Biology | 货号 |
AMM02831G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality BECN1 Antibody.
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分子量 |
60kDa
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细胞定位 |
Antigen Cellular Localization:
Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Note=Interaction with ATG14 promotes translocation to autophagosomes. Expressed in dendrites and cell bodies of cerebellar Purkinje cells (By similarity)
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宿主 |
Mouse
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种属反应性 |
Human
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克隆号 |
2A4
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亚型 |
IgG1
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通用名 |
GT197
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基因ID |
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UniProt ID |
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功能 |
Plays a central role in autophagy (PubMed:23184933). Required for the abcission step in cytokinesis (PubMed:20208530). Protects against infection by a neurovirulent strain of Sindbis virus (PubMed:9765397). May play a role in antiviral host defense.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC, FC, E
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稀释方法 |
E~~1/10000
WB~~1/500 - 1/2000
IHC~~1/500 - 1/2000
FC~~1/200 - 1/400
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图像 |
Red: Control Antigen (100ng);Purple: Antigen (10ng);Green: Antigen (50ng);Blue: Antigen (100ng);
Figure 1: Western blot analysis using BECN1 mouse mAb against Hela (1), A431 (2), MCF-7 (3), RAJI (4), Jurkat (5) and SKBR-3 (6) cell lysate.
Figure 2: Immunohistochemical analysis of paraffin-embedded breast cancer tissues (left) and liver cancer tissues (right) using BECN1 mouse mAb with DAB staining. |
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说明书 |
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数量 |
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