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> 抗原抗体、ELISA、WB > 一抗 > Monoclonal Antibodies > CD79B Antibody (Intracellular, clone AT107-2)品牌 |
Leading Biology | 货号 |
AMRa00015G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CD79B Antibody (Intracellular, clone AT107-2).
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分子量 |
26kDa
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细胞定位 |
Antigen Cellular Localization:
Cell membrane; Single-pass type I membrane protein. Note=Following antigen binding, the BCR has been shown to translocate from detergent-soluble regions of the cell membrane to lipid rafts although signal transduction through the complex can also occur outside lipid rafts.
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宿主 |
Rat
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种属反应性 |
Human, Rat, Pig, Dog
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靶点 |
Recognizes an intracellular region of human and mouse CD79b, a cell surface antigen expressed by B lymphocytes. The CD79b molecule (also known as Ig beta and B29) associates with CD79a to form a heterodimer that is covalently linked to surface immuno ...
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克隆号 |
AT107-2
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通用名 |
B29, IGB
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基因ID |
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UniProt ID |
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功能 |
Required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation.
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总结 |
Required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, E, IP, Flo
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稀释方法 |
Flo (1:50-1:100), IHC-P (2 μg/ml),
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图像 |
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说明书 |
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数量 |
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