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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Monoclonal Antibodies > ZBTB7B / HcKrox Antibody (clone 7C12)

ZBTB7B / HcKrox Antibody (clone 7C12)

货号 货期 规格 / 价格 询价
AMM01889G 50 μl / ¥4950

ZBTB7B / HcKrox Antibody (clone 7C12)

品牌

Leading Biology

货号

AMM01889G

产品分类

Monoclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ZBTB7B / HcKrox Antibody (clone 7C12).

分子量

58kDa

细胞定位

Antigen Cellular Localization: Nucleus.

宿主

Mouse

种属反应性

Human

靶点

Human ZBTB7B

克隆号

7C12

通用名

ZBTB15, ZFP67, ZNF857B

基因ID

UniProt ID

功能

Transcription regulator that acts as a key regulator of lineage commitment of immature T-cell precursors. Necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. Development of immature T-cell precursors (thymocytes) to either the CD4 helper or CD8 killer T-cell lineages correlates precisely with their T-cell receptor specificity for major histocompatibility complex class II or class I molecules, respectively. Transcriptional repressor of the collagen COL1A1 and COL1A2 genes. May also function as a repressor of fibronectin and possibly other extracellular matrix genes (By similarity).

总结

Transcription regulator that acts as a key regulator of lineage commitment of immature T-cell precursors. Necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. Development of immature T-cell precursors (thymocytes) to either the CD4 helper or CD8 killer T-cell lineages correlates precisely with their T-cell receptor specificity for major histocompatibility complex class II or class I molecules, respectively. Transcriptional repressor of the collagen COL1A1 and COL1A2 genes. May also function as a repressor of fibronectin and possibly other extracellular matrix genes (By similarity).

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

WB, IHC-P, IF, E

稀释方法

IF (1:200-1:1000), IHC-P (1:200), WB (1:500-1:2000)

图像

Immunofluorescence of HeLa cells using ZBTB7B mouse monoclonal antibody (green).

Anti-ZBTB7B antibody IHC of human breast.

Anti-ZBTB7B antibody IHC of human placenta.

说明书

数量

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