全部产品分类
品牌 |
Leading Biology | 货号 |
AMM01886G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality RCHY1 / PIRH2 Antibody (clone 1H10).
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分子量 |
30kDa
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细胞定位 |
Antigen Cellular Localization:
Nucleus. Nucleus speckle. Cytoplasm.
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宿主 |
Mouse
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种属反应性 |
Human, Rat
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靶点 |
Human RCHY1
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克隆号 |
1H10
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通用名 |
ARNIP, CHIMP, PIRH2, RNF199, ZNF363
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基因ID |
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UniProt ID |
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功能 |
Mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including p53/TP53, P73, HDAC1 and CDKN1B. Preferentially acts on tetrameric p53/TP53. Monoubiquitinates the translesion DNA polymerase POLH. Contributes to the regulation of the cell cycle progression. Increases AR transcription factor activity.
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总结 |
Mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including p53/TP53, P73, HDAC1 and CDKN1B. Preferentially acts on tetrameric p53/TP53. Monoubiquitinates the translesion DNA polymerase POLH. Contributes to the regulation of the cell cycle progression. Increases AR transcription factor activity.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, IF, E, Flo
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稀释方法 |
ELISA (1:10000), Flo (1:200-1:400), IF (1:200-1:1000), IHC-P (1:200), WB (1:500-1:2000)
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图像 |
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说明书 |
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数量 |
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