全部产品分类
品牌 |
Leading Biology | 货号 |
AMM01872G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality FRK Antibody (clone 1A8H2C12).
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分子量 |
58kDa
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细胞定位 |
Antigen Cellular Localization:
Cytoplasm. Nucleus. Note=Predominantly found in the nucleus, with a small fraction found in the cell periphery
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宿主 |
Mouse
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种属反应性 |
Human
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靶点 |
Human FRK
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克隆号 |
1A8H2C12
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通用名 |
PTK5, RAK
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基因ID |
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UniProt ID |
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功能 |
Non-receptor tyrosine-protein kinase that negatively regulates cell proliferation. Positively regulates PTEN protein stability through phosphorylation of PTEN on 'Tyr-336', which in turn prevents its ubiquitination and degradation, possibly by reducing its binding to NEDD4. May function as a tumor suppressor.
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总结 |
Non-receptor tyrosine-protein kinase that negatively regulates cell proliferation. Positively regulates PTEN protein stability through phosphorylation of PTEN on 'Tyr-336', which in turn prevents its ubiquitination and degradation, possibly by reducing its binding to NEDD4. May function as a tumor suppressor.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, E
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稀释方法 |
ELISA (1:10000), IHC-P (1:200), WB (1:500-1:2000)
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图像 |
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说明书 |
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数量 |
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