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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Monoclonal Antibodies > CUL9 / Cullin 9 Antibody (clone PO69)

CUL9 / Cullin 9 Antibody (clone PO69)

货号 货期 规格 / 价格 询价
AMM01866G 50 μg / ¥4950

CUL9 / Cullin 9 Antibody (clone PO69)

品牌

Leading Biology

货号

AMM01866G

产品分类

Monoclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CUL9 / Cullin 9 Antibody (clone PO69).

分子量

281kDa

细胞定位

Antigen Cellular Localization: Cytoplasm.

宿主

Mouse

种属反应性

Human, Mouse

靶点

Human PARC peptide, corresponding to human amino acids AWEAKGPNMPGSC

克隆号

PO69

通用名

H7AP1, KIAA0708, PARC

基因ID

UniProt ID

功能

Core component of a Cul9-RING ubiquitin-protein ligase complex, a complex that mediates ubiquitination and subsequent degradation of BIRC5 and is required to maintain microtubule dynamics and genome integrity. Acts downstream of the 3M complex, which inhibits CUL9 activity, leading to prevent ubiquitination of BIRC5 (PubMed:24793696). Cytoplasmic anchor protein in p53/TP53- associated protein complex. Regulates the subcellular localization of p53/TP53 and subsequent function (PubMed:12526791, PubMed:17332328).

总结

Core component of a Cul9-RING ubiquitin-protein ligase complex, a complex that mediates ubiquitination and subsequent degradation of BIRC5 and is required to maintain microtubule dynamics and genome integrity. Acts downstream of the 3M complex, which inhibits CUL9 activity, leading to prevent ubiquitination of BIRC5 (PubMed:24793696). Cytoplasmic anchor protein in p53/TP53- associated protein complex. Regulates the subcellular localization of p53/TP53 and subsequent function (PubMed:12526791, PubMed:17332328).

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

WB, IHC-P

稀释方法

IHC-P (10 μg/ml)

图像

HepG2 cell extract (left lane) or NIH 3T3 cell extract (right lane) probed with monoclonal...

Anti-CUL9 / Cullin 9 antibody IHC of human placenta.

Anti-CUL9 / Cullin 9 antibody IHC of human prostate.

说明书

数量

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