> 抗原抗体、ELISA、WB > 一抗 > Monoclonal Antibodies > RBBP4 / RBAP48 Antibody (aa1-425, clone 11G10)品牌 |
Leading Biology | 货号 |
AMM01715G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality RBBP4 / RBAP48 Antibody (aa1-425, clone 11G10).
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分子量 |
48kDa
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细胞定位 |
Antigen Cellular Localization:
Nucleus.
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宿主 |
Mouse
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种属反应性 |
Human, Mouse
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靶点 |
The complete coding region (amino acids 1-425) of RbAp48 expressed in E. coli.
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克隆号 |
11G10
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通用名 |
RBAP48
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基因ID |
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UniProt ID |
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功能 |
Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the chromatin assembly factor 1 (CAF-1) complex, which is required for chromatin assembly following DNA replication and DNA repair; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome remodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling; the PRC2/EED-EZH2 complex, which promotes repression of homeotic genes during development; and the NURF (nucleosome remodeling factor) complex.
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总结 |
Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the chromatin assembly factor 1 (CAF-1) complex, which is required for chromatin assembly following DNA replication and DNA repair; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome remodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling; the PRC2/EED-EZH2 complex, which promotes repression of homeotic genes during development; and the NURF (nucleosome remodeling factor) complex.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, IF, IP
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稀释方法 |
IHC-P (5 μg/ml)
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图像 |
Anti-RBBP4 / RBAP48 antibody IHC of human testis. |
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说明书 |
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数量 |
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