品牌 |
Leading Biology | 货号 |
AMM04246G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality TRIM25 Antibody (monoclonal) (M02).
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分子量 |
70973 Da
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宿主 |
mouse
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种属反应性 |
Human
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靶点 |
TRIM25 (NP_005073, 211 a.a. ~ 310 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
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克隆号 |
5F12
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亚型 |
IgG1 Kappa
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基因ID |
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UniProt ID |
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总结 |
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. The presence of potential DNA-binding and dimerization-transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IF
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稀释方法 |
WB~~1:500~1000
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图像 |
TRIM25 monoclonal antibody (M02), clone 5F12 Western Blot analysis of TRIM25 expression in Hela S3 NE (AMM04246G ).
Immunofluorescence of monoclonal antibody to TRIM25 on HeLa cell. [antibody concentration 10 ug/ml] |
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说明书 |
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数量 |
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