品牌 |
Leading Biology | 货号 |
AMM04240G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality TRADD Antibody (monoclonal) (M01).
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分子量 |
34247 Da
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宿主 |
mouse
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种属反应性 |
Human
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靶点 |
TRADD (NP_003780, 203 a.a. ~ 312 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
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克隆号 |
3G1
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亚型 |
IgG2a Kappa
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基因ID |
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UniProt ID |
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总结 |
The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IF
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稀释方法 |
WB~~1:500~1000
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图像 |
TRADD monoclonal antibody (M01), clone 3G1. Western Blot analysis of TRADD expression in Hela S3 NE (AMM04240G).
Immunofluorescence of monoclonal antibody to TRADD on HeLa cell . [antibody concentration 20 ug/ml] |
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说明书 |
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数量 |
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