品牌 |
Leading Biology | 货号 |
AMM04222G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality TNNC1 Antibody (monoclonal) (M01).
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分子量 |
18403 Da
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宿主 |
mouse
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种属反应性 |
Human
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靶点 |
TNNC1 (AAH30244, 1 a.a. ~ 161 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
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克隆号 |
1F8-A9
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亚型 |
IgG1 kappa
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基因ID |
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UniProt ID |
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总结 |
Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase; TnT, which contains the binding site for tropomyosin; and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension. Mutations in this gene are associated with cardiomyopathy dilated type 1Z.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC, E
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稀释方法 |
WB~~1:500~1000
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图像 |
Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (43.45 KDa) .
Western Blot analysis of TNNC1 expression in transfected 293T cell line by TNNC1 monoclonal antibody (M01), clone 1F8-A9.Lane 1: TNNC1 transfected lysate(18.4 KDa).Lane 2: Non-transfected lysate.
Immunoperoxidase of monoclonal antibody to TNNC1 on formalin-fixed paraffin-embedded human heart. [antibody concentration 3 ug/ml] |
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说明书 |
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数量 |
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