品牌 |
Leading Biology | 货号 |
AMM03874G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality OTUB1 Antibody (monoclonal) (M09).
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分子量 |
31284 Da
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宿主 |
Mouse
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种属反应性 |
Human
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靶点 |
OTUB1 (AAH07519, 1 a.a. ~ 271 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
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克隆号 |
1C12
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亚型 |
IgG2a Kappa
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基因ID |
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UniProt ID |
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总结 |
The product of this gene is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function for polyubiquitin chain growth. Alternative splicing results in multiple transcript variants.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:500~1000
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图像 |
OTUB1 monoclonal antibody (M09), clone 1C12. Western Blot analysis of OTUB1 expression in Hela S3 NE ( AMM03874G ).
Detection limit for recombinant GST tagged OTUB1 is 1 ng/ml as a capture antibody. |
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说明书 |
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数量 |
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