品牌 |
Leading Biology | 货号 |
AMM03617G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality HERPUD1 Antibody (monoclonal) (M01).
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分子量 |
43720 Da
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宿主 |
mouse
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种属反应性 |
Human
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靶点 |
HERPUD1 (AAH00086, 1 a.a. ~ 391 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
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克隆号 |
3.00E+11
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亚型 |
IgG1 kappa
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基因ID |
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UniProt ID |
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总结 |
The accumulation of unfolded proteins in the endoplasmic reticulum (ER) triggers the ER stress response. This response includes the inhibition of translation to prevent further accumulation of unfolded proteins, the increased expression of proteins involved in polypeptide folding, known as the unfolded protein response (UPR), and the destruction of misfolded proteins by the ER-associated protein degradation (ERAD) system. This gene may play a role in both UPR and ERAD. Its expression is induced by UPR and it has an ER stress response element in its promoter region while the encoded protein has an N-terminal ubiquitin-like domain which may interact with the ERAD system. This protein has been shown to interact with presenilin proteins and to increase the level of amyloid-beta protein following its overexpression. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms. The full-length nature of all transcript variants has not been determined.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:500~1000
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图像 |
Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (68.75 KDa) .
Western Blot analysis of HERPUD1 expression in transfected 293T cell line by HERPUD1 monoclonal antibody (M01), clone 3E10.Lane 1: HERPUD1 transfected lysate(44 KDa).Lane 2: Non-transfected lysate.
Detection limit for recombinant GST tagged HERPUD1 is approximately 0.3ng/ml as a capture antibody. |
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说明书 |
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数量 |
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