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> 抗原抗体、ELISA、WB > 一抗 > Monoclonal Antibodies > Placental Alkaline Phosphatase (PLAP) (Germ Cell Tumor Marker) Antibody - Without BSA and Azide品牌 |
Leading Biology | 货号 |
AMM00714G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Placental Alkaline Phosphatase (PLAP) (Germ Cell Tumor Marker) Antibody - Without BSA and Azide.
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分子量 |
70kDa
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细胞定位 |
Antigen Cellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor.
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宿主 |
Mouse
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种属反应性 |
Human
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克隆号 |
SPM593
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亚型 |
Mouse / IgG2b, kappa
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通用名 |
PLAP
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基因ID |
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UniProt ID |
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总结 |
Reacts with a 70kDa membrane-bound isozyme (Regan and Nagao type) of Placental Alkaline Phosphatase (PLAP) occurring in the placenta during the 3rd trimester of gestation. It is highly specific for PLAP and shows no cross-reaction with other isozymes of alkaline phosphatase. Anti-PLAP reacts with germ cell tumors and can discriminate between these and other neoplasms. Somatic neoplasms e.g. breast, gastrointestinal, prostatic, and urinary cancers may also immunoreact with antibodies to PLAP. Anti-PLAP positivity in conjunction with anti-keratin negativity favors seminoma over carcinoma. Germ cell tumors are usually anti-keratin positive, but they regularly fail to stain with anti-EMA, whereas most carcinomas stain with anti-EMA. Anti-PLAP has been useful in the diagnosis of gestational trophoblastic disease.?
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形式 |
Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
IHC, IF, FC
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图像 |
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说明书 |
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数量 |
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