> 抗原抗体、ELISA、WB > 一抗 > Monoclonal Antibodies > IgA Secretory Component / ECM1 Antibody - Without BSA and Azide品牌 |
Leading Biology | 货号 |
AMM00247G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality IgA Secretory Component / ECM1 Antibody - Without BSA and Azide.
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分子量 |
~80kDa
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细胞定位 |
Antigen Cellular Localization:
Secreted, extracellular space, extracellular matrix
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宿主 |
Mouse
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种属反应性 |
Human, Rat
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克隆号 |
SC05
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亚型 |
Mouse / IgG1, kappa
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基因ID |
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UniProt ID |
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功能 |
Involved in endochondral bone formation as negative regulator of bone mineralization. Stimulates the proliferation of endothelial cells and promotes angiogenesis. Inhibits MMP9 proteolytic activity.
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总结 |
This MAb reacts with a reduction-resistant epitope present in both free and SIgA bound Secretory Component. It does not react with the cell lines lacking secretory component. The antibody is useful for studying the distribution and level of both free and bound secretory component. Secretory component is differentially expressed in epithelium, and the antibody is a popular marker for identifying subpopulations of epithelial cells and epithelial differentiation. The Secretory component antibody is a useful research tool for studying mucosal immunity, inflammation, remodeling, differentiation and tumorigenesis, all processes associated with differential secretory component expression.
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形式 |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
IHC-P, IF, FC
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图像 |
Formalin-fixed, paraffin-embedded human Colon Carcinoma stained with IgA Secretory Component Monoclonal Antibody (SC-05). |
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说明书 |
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数量 |
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