全部产品分类
品牌 |
Leading Biology | 货号 |
AMM01684G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Cytokeratin 8/18 Antibody.
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分子量 |
52.5kDa (CK8); 45kDa (CK18)
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细胞定位 |
Antigen Cellular Localization:
Cytoplasm. Nucleus, nucleoplasm Nucleus matrix
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宿主 |
Mouse
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种属反应性 |
Human
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克隆号 |
K8.8 + DC10
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亚型 |
Mouse / IgG's
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通用名 |
CYK8
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基因ID |
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UniProt ID |
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功能 |
Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.
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总结 |
Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). This MAb cocktail recognizes all simple epithelia including glandular epithelium, for example thyroid, female breast, gastrointestinal tract, respiratory tract, and urogenital tract including transitional epithelium. All adenocarcinomas and most squamous carcinomas are positive but keratinizing squamous carcinomas are usually negative. This antibody is useful in demonstrating the presence of Paget cells; there is very little keratin 18 in the normal epidermis so only Paget cells are stained.?Immunohistochemical staining with this MAb is indistinguishable from that obtained with monoclonal antibody 5D3.
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形式 |
Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC, IF, FC
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图像 |
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说明书 |
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数量 |
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