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> 抗原抗体、ELISA、WB > 一抗 > Monoclonal Antibodies > CD57 / B3GAT1 (Natural Killer Cell Marker) Antibody品牌 |
Leading Biology | 货号 |
AMM00746G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CD57 / B3GAT1 (Natural Killer Cell Marker) Antibody.
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分子量 |
~110kDa
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细胞定位 |
Antigen Cellular Localization:
Golgi apparatus membrane; Single-pass type II membrane protein
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宿主 |
Mouse
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种属反应性 |
Human
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克隆号 |
HNK-1 or Leu-7
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亚型 |
Mouse / IgM, kappa
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通用名 |
GLCATP
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基因ID |
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UniProt ID |
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功能 |
Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo- orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl- sphingomyelin was the most effective, followed by palmitoyl- sphingomyelin and lignoceroyl-sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group (By similarity).
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总结 |
Anti-CD57 marks a subset of lymphocytes known as natural killer (NK) cells. Follicular center cell lymphomas often contain many NK cells within the neoplastic follicles. Anti-CD57 also stains neuroendocrine cells and their derived tumors, including carcinoid tumor and medulloblastoma. Anti-CD57 can also be useful in separating type B3 thymoma from thymic carcinoma when combined with a panel that includes antibodies against GLUT1, CD5, and CEA.
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形式 |
Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
IHC, IF
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图像 |
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说明书 |
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数量 |
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