品牌 |
Leading Biology | 货号 |
AMM02566G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality RAB21 Antibody.
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分子量 |
24348 Da
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细胞定位 |
Antigen Cellular Localization:
Endoplasmic reticulum membrane; Lipid-anchor. Golgi apparatus, trans- Golgi network. Golgi apparatus membrane. Early endosome membrane. Cytoplasmic vesicle membrane Cleavage furrow. Note=Colocalizes with ANKRD27 and VAMP7 in neurites (By similarity). In nonpolarized epithelial Caco-2 cells, found in the endoplasmic reticulum; in polarized cells, observed in vesicles in the apical cytoplasm. During mitosis, in mid- telophase, localized in the ingressing cleavage furrow. In late telophase, detected at the opposite poles of the daughter cells, in vesicles at the base of lamellipodia formed by the separating daughter cells. {ECO:0000250|UniProtKB:P35282, ECO:0000250|UniProtKB:Q6AXT5}
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宿主 |
Mouse
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种属反应性 |
Human, African Green Monkey
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靶点 |
This RAB21 antibody is generated from a mouse immunized with a recombinant protein between 1-225 amino acids from the human RAB21.
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克隆号 |
1701CT536.68.39
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亚型 |
IgG2b,κ
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通用名 |
KIAA0118
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基因ID |
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UniProt ID |
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功能 |
Regulates integrin internalization and recycling, but does not influence the traffic of endosomally translocated receptors in general. As a result, may regulate cell adhesion and migration (By similarity). During the mitosis of adherent cells, controls the endosomal trafficking of integrins which is required for the successful completion of cytokinesis. Involved in neurite growth (By similarity).
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总结 |
Regulates integrin internalization and recycling, but does not influence the traffic of endosomally translocated receptors in general. As a result, may regulate cell adhesion and migration (By similarity). During the mitosis of adherent cells, controls the endosomal trafficking of integrins which is required for the successful completion of cytokinesis. Involved in neurite growth (By similarity).
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:2000
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图像 |
All lanes : Anti-RAB21 Antibody at 1:2000 dilution Lane 1: MCF-7 whole cell lysate Lane 2: A431 whole cell lysate Lane 3: Hela whole cell lysate Lane 4: COS-7 whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 24 kDa Blocking/Dilution buffer: 5% NFDM/TBST. |
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说明书 |
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数量 |
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