品牌 |
Leading Biology | 货号 |
AMM02517G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CAPN6 Antibody.
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分子量 |
74576 Da
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细胞定位 |
Antigen Cellular Localization:
Cytoplasm, perinuclear region. Cytoplasm, cytoskeleton, spindle. Note=During mitose associated with the mitotic spindle. At telophase colocalized to the midbody spindle
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宿主 |
Mouse
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种属反应性 |
Mouse
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靶点 |
This CAPN6 antibody is generated from a mouse immunized with a recombinant protein of human CAPN6.
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克隆号 |
1395CT446.22.5
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亚型 |
IgG1
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通用名 |
CALPM, CANPX
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基因ID |
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UniProt ID |
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功能 |
Microtubule-stabilizing protein that may be involved in the regulation of microtubule dynamics and cytoskeletal organization. May act as a regulator of RAC1 activity through interaction with ARHGEF2 to control lamellipodial formation and cell mobility. Does not seem to have protease activity as it has lost the active site residues (By similarity).
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总结 |
Microtubule-stabilizing protein that may be involved in the regulation of microtubule dynamics and cytoskeletal organization. May act as a regulator of RAC1 activity through interaction with ARHGEF2 to control lamellipodial formation and cell mobility. Does not seem to have protease activity as it has lost the active site residues (By similarity).
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
FC, WB, E
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稀释方法 |
FC~~1:25
WB~~1:1000
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图像 |
Flow cytometric analysis of A549 cells using CAPN6 Antibody(green, AMM02517G) compared to an isotype control of mouse IgG1(blue). was diluted at 1:25 dilution. An Alexa Fluor? 488 goat anti-mouse lgG at 1:400 dilution was used as the secondary antibody.
Western blot analysis of lysate from human placenta tissue lysate, using CAPN6 Antibody(AMM02517G). AMM02517G was diluted at 1:1000. A goat anti-mouse IgG H&L(HRP) at 1:3000 dilution was used as the secondary antibody. Lysate at 20μg. |
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说明书 |
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数量 |
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