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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Monoclonal Antibodies > VWF Antibody

VWF Antibody

货号 货期 规格 / 价格 询价
AMM02506G 100 μl / ¥4950

VWF Antibody

品牌

Leading Biology

货号

AMM02506G

产品分类

Monoclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality VWF Antibody.

分子量

309265 Da

细胞定位

Antigen Cellular Localization: Secreted. Secreted, extracellular space, extracellular matrix. Note=Localized to storage granules

宿主

Mouse

种属反应性

Human

靶点

This antibody is generated from a mouse immunized with .VWF recombinant protein.

克隆号

907CT12.1.9

亚型

IgG1

通用名

F8VWF

基因ID

UniProt ID

功能

Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma.

总结

Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma.

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

WB, IHC-P, FC, E

稀释方法

FC~~1:100 IHC-P~~1:25 WB~~1:1000

图像

Flow cytometric analysis of K562 cells using VWF(green, AMM02506G) compared to an isotype control of mouse IgG1(blue). AP20600c was diluted at 1:100 dilution. An Alexa Fluor? 488 goat anti-mouse lgG at 1:400 dilution was used as the secondary antibody.

Immunohistochemical analysis of paraffin-embedded H. kidney section using VWF( AMM02506G). AMM02506G was diluted at 1:25 dilution. A peroxidase-conjugated goat anti-mouse IgG at 1:400 dilution was used as the secondary antibody, followed by DAB staining.

Western blot analysis of lysate from VWF protein, using VWF Antibody(AMM02506G). AMM02506G was diluted at 1:1000. A goat anti-mouse IgG H&L(HRP) at 1:3000 dilution was used as the secondary antibody. Lysate at 35μg.

说明书

数量

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