全部产品分类
品牌 |
Leading Biology | 货号 |
AMM02445G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality LOX Antibody (Center).
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分子量 |
46944 Da
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细胞定位 |
Antigen Cellular Localization:
Secreted, extracellular space.
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宿主 |
Mouse
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种属反应性 |
Human
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免疫原 |
234-260 aa
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靶点 |
This LOX antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 234-260 amino acids from the Central region of human LOX.
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克隆号 |
624CT23.7.3
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亚型 |
IgG2b
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基因ID |
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UniProt ID |
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功能 |
Responsible for the post-translational oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin. In addition to cross-linking of extracellular matrix proteins, may have a direct role in tumor suppression.
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总结 |
The protein encoded by this gene is an extracellularcopper enzyme that initiates the crosslinking of collagens andelastin. The enzyme catalyzes oxidative deamination of theepsilon-amino group in certain lysine and hydroxylysine residues ofcollagens and lysine residues of elastin. In addition tocrosslinking extracellular matrix proteins, the encoded protein mayhave a role in tumor suppression. Defects in this gene are a causeof autosomal recessive cutis laxa type I (CL type I). Twotranscript variants encoding different isoforms have been found forthis gene.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:100~500
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图像 |
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说明书 |
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数量 |
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