全部产品分类
品牌 |
Leading Biology | 货号 |
AMM02383G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Mouse Bmi1 Antibody.
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分子量 |
36708 Da
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细胞定位 |
Antigen Cellular Localization:
Nucleus. Cytoplasm.
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宿主 |
Mouse
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种属反应性 |
Mouse
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免疫原 |
136-163 aa
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靶点 |
This Mouse Bmi1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 136-163 amino acids from mouse Bmi1.
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克隆号 |
353CT22.4.4
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亚型 |
IgG2b
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通用名 |
Bmi-1, Pcgf4
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基因ID |
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UniProt ID |
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功能 |
Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2 (By similarity).
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总结 |
Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility (By similarity). In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:200~1600
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图像 |
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说明书 |
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数量 |
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