全部产品分类
品牌 |
Leading Biology | 货号 |
AMM02381G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality MMP9 Antibody (Ascites).
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分子量 |
78458 Da
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细胞定位 |
Antigen Cellular Localization:
Secreted, extracellular space, extracellular matrix
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宿主 |
Mouse
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种属反应性 |
Human
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靶点 |
Purified His-tagged MMP9 protein(Fragment) was used to produced this monoclonal antibody.
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克隆号 |
331CT17.4.4
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亚型 |
IgM
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通用名 |
CLG4B
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基因ID |
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UniProt ID |
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功能 |
May play an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-|-Leu bond. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide.
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总结 |
Proteins of the matrix metalloproteinase (MMP) family areinvolved in the breakdown of extracellular matrix in normalphysiological processes, such as embryonic development,reproduction, and tissue remodeling, as well as in diseaseprocesses, such as arthritis and metastasis. Most MMP's aresecreted as inactive proproteins which are activated when cleavedby extracellular proteinases. The enzyme encoded by this genedegrades type IV and V collagens. Studies in rhesus monkeys suggestthat the enzyme is involved in IL-8-induced mobilization ofhematopoietic progenitor cells from bone marrow, and murine studiessuggest a role in tumor-associated tissue remodeling. [provided byRefSeq].
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:500~8000
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图像 |
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说明书 |
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数量 |
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