全部产品分类
品牌 |
Leading Biology | 货号 |
AMM02343G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CDCA8 Antibody.
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分子量 |
31323 Da
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细胞定位 |
Antigen Cellular Localization:
Nucleus, nucleolus. Cytoplasm. Cytoplasm, cytoskeleton, spindle. Chromosome, centromere. Note=Localizes on chromosome arms and inner centromeres from prophase through metaphase and then transferring to the spindle midzone and midbody from anaphase through cytokinesis. Colocalizes with SENP3 in the nucleolus in interphase cells
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宿主 |
Mouse
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种属反应性 |
Human
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靶点 |
This CDCA8 monoclonal antibody is generated from mouse immunized with CDCA8 recombinant protein.
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克隆号 |
181CT41.2.3
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亚型 |
IgG1,K
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通用名 |
PESCRG3
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基因ID |
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UniProt ID |
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功能 |
Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. In the complex, it may be required to direct the CPC to centromeric DNA. Major effector of the TTK kinase in the control of attachment-error-correction and chromosome alignment.
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总结 |
CDCA8 is a component of a chromosomal passenger complexrequired for stability of the bipolar mitotic spindle (Gassmann etal., 2004 [PubMed 15249581]).
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:100~500
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图像 |
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说明书 |
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数量 |
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