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> 抗原抗体、ELISA、WB > 一抗 > Monoclonal Antibodies > HSP27 (Heat Shock Protein 27) Antibody - With BSA and Azide品牌 |
Leading Biology | 货号 |
AMM00112G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality HSP27 (Heat Shock Protein 27) Antibody - With BSA and Azide.
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分子量 |
27kDa
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细胞定位 |
Antigen Cellular Localization:
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle. Note=Cytoplasmic in interphase cells. Colocalizes with mitotic spindles in mitotic cells. Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles
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宿主 |
Mouse
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种属反应性 |
Human, Mouse, Rat
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靶点 |
Partially purified hsp27 (earlier called 24K) protein from breast cancer MCF-7 cells.
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克隆号 |
G3.1
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亚型 |
IgG1, kappa
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通用名 |
HSP27, HSP28
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基因ID |
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UniProt ID |
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功能 |
Involved in stress resistance and actin organization.
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总结 |
It recognizes a 24-27kDa estrogen-regulated protein, identified as heat shock protein 27 (hsp27). Hsp27 was recently found to be identical to the estrogen-induced “p29” and “24K” protein. About 50% of breast carcinomas are positive for hsp27 especially those that are also positive for estrogen and/or progesterone receptor. HSP27 has also been implicated in drug resistance in cancer cells.
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形式 |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC, IF, FC, IP, E
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图像 |
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说明书 |
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数量 |
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