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> 抗原抗体、ELISA、WB > 一抗 > Monoclonal Antibodies > MUC5AC (Mucin 5AC / Gastric Mucin) Antibody - With BSA and Azide品牌 |
Leading Biology | 货号 |
AMM00050G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality MUC5AC (Mucin 5AC / Gastric Mucin) Antibody - With BSA and Azide.
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分子量 |
>1,000kDa
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细胞定位 |
Antigen Cellular Localization:
Secreted.
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宿主 |
Mouse
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种属反应性 |
Human, Mouse, Rat
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靶点 |
M1 mucin preparation from the fluid of an ovarian mucinous cyst belonging to an O Le(a-b) patient
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克隆号 |
45M1
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亚型 |
IgG1, kappa
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通用名 |
MUC5
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UniProt ID |
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功能 |
Gel-forming glycoprotein of gastric and respiratoy tract epithelia that protects the mucosa from infection and chemical damage by binding to inhaled microrganisms and particles that are subsequently removed by the mucocilary system.
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总结 |
This MAb recognizes the peptide core of gastric mucin M1 (>1,000kDa) (recently identified as Mucin 5AC). Its epitope is destroyed by beta-mercaptoethanol and proteases but not by periodate treatment. Antibody to gastric mucin M1 reacts with the gastric epithelium of normal human gastrointestinal tract as well as with the precancerous and cancerous colon but not with normal adult colon. It also reacts with fetal colonic mucosa. Resurgence of gastric mucin reactivity during colonic carcinogenesis is due to re-expression of the peptide core of gastric (or fetal colonic) mucins.
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形式 |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC, FC, IP, E
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图像 |
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说明书 |
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数量 |
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