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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > 单克隆抗体 > DUX4 Antibody (clone P2B1)

DUX4 Antibody (clone P2B1)

LM21223
货号 货期 规格 / 价格 询价

DUX4 Antibody (clone P2B1)

品牌

Leading Biology

货号

LM21223

产品分类

单克隆抗体

研究领域

形式

Involved in transcriptional regulation. May regulate microRNA (miRNA) expression.

浓度

This antibody recognizeshuman DUX4. It does notcross-react with DUX4c.

纯度

Mouse

复溶

Gabrieels J.,et al.Gene 236:25-32(1999). Leclercq I.,et al.Submitted (JUN-2001) to the EMBL/GenBank/DDBJ databases. Hillier L.W.,et al.Nature 434:724-731(2005). Oestlund C.,et al.Biochemistry 44:2378-2384(2005). Mostacciuolo M.L.,et al.Clin. Genet. 75:550-555(2009).

储存条件

Human

储存溶液

Double homeobox protein 4 {ECO:0000312|HGNC:HGNC:50800}, Double homeobox protein 10 {ECO:0000312|EMBL:AAK91509.1}, DUX4 (HGNC:50800), DUX10

应用

IHC-P (10 μg/ml), WB (1:1000),

产品描述

Function Involved in transcriptional regulation. May regulate microRNA (miRNA) expression. Cellular_Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108, ECO:0000269|PubMed:15709750, ECO:0000269|PubMed:21060811}. Note=Actively transported through the nuclear pore complex (NPC) Tissue_Location Does not seem to be expressed in normal muscle, but is detected in muscle of individuals with FSHD, and also in testis (at protein level) (PubMed:21060811). Does not seem to be expressed in normal muscle, but in muscle of individuals with FSHD, where it may be toxic to cells

数量

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