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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > 单克隆抗体 > Tyk2 Antibody

Tyk2 Antibody

LM21163
货号 货期 规格 / 价格 询价

Tyk2 Antibody

品牌

Leading Biology

货号

LM21163

产品分类

单克隆抗体

研究领域

产品概述

Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

形式

Novel non-receptor tyrosine-protein kinase, Tyk2, belongs to the tyrosine protein kinase family and plays a role in intracellular signal transduction by being involved in the initiation of type I IFN signaling. Tyk2 is believed to phosphorylate the interferon-alpha/beta receptor alpha chain (1). It has been shown that Tyk2 links the interferon alpha/beta receptor to the cytoplasmic transcription factor that mediates activation of interferon-responsive genes (2).

浓度

A synthetic peptide corresponding to residues near the C-terminus of human Tyk2 was used as an immunogen.

纯度

Rabbit

试剂准备

50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.

复溶

1. Firmback-Kraft I, et al. Oncogene 5(9):1329-36, 1990.<br>2. Velazquez L, et al. Cell 70(2):313-22, 1992.<br>

储存条件

Human, Mouse, Rat

储存溶液

Non-receptor tyrosine-protein kinase TYK2, TYK2

应用

WB~~1:1000~5000 IHC~~1:100~250

产品描述

Function Probably involved in intracellular signal transduction by being involved in the initiation of type I IFN signaling. Phosphorylates the interferon-alpha/beta receptor alpha chain. Tissue_Location Observed in all cell lines analyzed. Expressed in a variety of lymphoid and non-lymphoid cell lines

数量

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