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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > 单克隆抗体 > TLN1 Antibody (monoclonal) (M05)

TLN1 Antibody (monoclonal) (M05)

LM21117
货号 货期 规格 / 价格 询价

TLN1 Antibody (monoclonal) (M05)

品牌

Leading Biology

货号

LM21117

产品分类

单克隆抗体

研究领域

产品概述

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

形式

This gene encodes a cytoskeletal protein that is concentrated in areas of cell-substratum and cell-cell contacts. The encoded protein plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. It codistributes with integrins in the cell surface membrane in order to assist in the attachment of adherent cells to extracellular matrices and of lymphocytes to other cells. The N-terminus of this protein contains elements for localization to cell-extracellular matrix junctions. The C-terminus contains binding sites for proteins such as beta-1-integrin, actin, and vinculin.

浓度

TLN1 (NP_006280, 1052 a.a. ~ 1149 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

纯度

mouse

试剂准备

Clear, colorless solution in phosphate buffered saline, pH 7.2.

复溶

Zap70 controls the interaction of talin with integrin to regulate the chemotactic directionality of T-cell migration. Lin YP, et al. Mol Immunol, 2010 Jul. PMID 20488542.Talin1 promotes tumor invasion and metastasis via focal adhesion signaling and anoikis resistance. Sakamoto S, et al. Cancer Res, 2010 Mar 1. PMID 20160039.Functional and structural characterization of the talin F0F1 domain. Domadia PN, et al. Biochem Biophys Res Commun, 2010 Jan 1. PMID 19903453.GATA-1, G208S macrothrombocytes are deficient in talin: immunofluorescence studies. White JG, et al. Platelets, 2009 May. PMID 19437340.Dystrophin-glycoprotein complex and vinculin-talin-integrin system in human adult cardiac muscle. Anastasi G, et al. Int J Mol Med, 2009 Feb. PMID 19148538.

储存条件

Human, Mouse, Rat

储存溶液

Talin-1, TLN1, KIAA1027, TLN

应用

WB~~1:500~1000

数量

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