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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > 单克隆抗体 > TCOF1 Antibody (monoclonal) (M02)

TCOF1 Antibody (monoclonal) (M02)

LM21089
货号 货期 规格 / 价格 询价

TCOF1 Antibody (monoclonal) (M02)

品牌

Leading Biology

货号

LM21089

产品分类

单克隆抗体

研究领域

产品概述

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

形式

This gene encodes a nucleolar protein with a LIS1 homology domain. The protein is involved in ribosomal DNA gene transcription through its interaction with upstream binding factor (UBF). Mutations in this gene have been associated with Treacher Collins syndrome, a disorder which includes abnormal craniofacial development. Multiple transcript variants encoding different isoforms have been found for this gene.

浓度

TCOF1 (NP_001008657, 2 a.a. ~ 82 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

纯度

mouse

试剂准备

Clear, colorless solution in phosphate buffered saline, pH 7.2.

复溶

Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia. Jugessur A, et al. PLoS One, 2010 Jul 9. PMID 20634891.New genetic associations detected in a host response study to hepatitis B vaccine. Davila S, et al. Genes Immun, 2010 Apr. PMID 20237496.Reduced transcription of TCOF1 in adult cells of Treacher Collins syndrome patients. Masotti C, et al. BMC Med Genet, 2009 Dec 14. PMID 20003452.Defining the human deubiquitinating enzyme interaction landscape. Sowa ME, et al. Cell, 2009 Jul 23. PMID 19615732.Treacle recruits RNA polymerase I complex to the nucleolus that is independent of UBF. Lin CI, et al. Biochem Biophys Res Commun, 2009 Aug 21. PMID 19527688.

储存条件

Human

储存溶液

Treacle protein, Treacher Collins syndrome protein, TCOF1

应用

WB~~1:500~1000

数量

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