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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > 单克隆抗体 > STC2 Antibody

STC2 Antibody

LM21053
货号 货期 规格 / 价格 询价

STC2 Antibody

品牌

Leading Biology

货号

LM21053

产品分类

单克隆抗体

研究领域

产品概述

Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

形式

This gene encodes a secreted, homodimeric glycoproteinthat is expressed in a wide variety of tissues and may haveautocrine or paracrine functions. The encoded protein has 10 of its15 cysteine residues conserved among stanniocalcin family membersand is phosphorylated by casein kinase 2 exclusively on its serineresidues. Its C-terminus contains a cluster of histidine residueswhich may interact with metal ions. The protein may play a role inthe regulation of renal and intestinal calcium and phosphatetransport, cell metabolism, or cellular calcium/phosphatehomeostasis. Constitutive overexpression of human stanniocalcin 2in mice resulted in pre- and postnatal growth restriction, reducedbone and skeletal muscle growth, and organomegaly. Expression ofthis gene is induced by estrogen and altered in some breastcancers.

浓度

This STC2 monoclonal antibody is generated from mouse immunized with STC2 recombinant protein.

纯度

Mouse

试剂准备

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

复溶

Yokoyama, K., et al. Nephron Clin Pract 115 (4), C237-C243 (2010) : Law, A.Y., et al. Exp. Cell Res. 316(3):466-476(2010) Volland, S., et al. Int. J. Cancer 125(9):2049-2057(2009) Ieta, K., et al. Int. J. Cancer 125(4):926-931(2009) Tamura, K., et al. Cancer Sci. 100(5):914-919(2009)

储存条件

Human

储存溶液

Stanniocalcin-2, STC-2, Stanniocalcin-related protein, STC-related protein, STCRP, STC2

应用

WB~~1:100~250

产品描述

Function Has an anti-hypocalcemic action on calcium and phosphate homeostasis. Cellular_Location Secreted. Tissue_Location Expressed in a variety of tissues including muscle, heart, pancreas, kidney, spleen, prostate, small intestine, colon and peripheral blood leukocytes

数量

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