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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > 单克隆抗体 > SPN/CD43 Antibody (N-term)

SPN/CD43 Antibody (N-term)

LM21038
货号 货期 规格 / 价格 询价

SPN/CD43 Antibody (N-term)

品牌

Leading Biology

货号

LM21038

产品分类

单克隆抗体

研究领域

产品概述

Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

形式

Sialophorin (leukosialin) is a major sialoglycoprotein onthe surface of human T lymphocytes, monocytes, granulocytes, andsome B lymphocytes, which appears to be important for immunefunction and may be part of a physiologic ligand-receptor complexinvolved in T-cell activation.

浓度

This SPN/CD43 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 230-257 amino acids from the N-terminal region of human SPN/CD43.

纯度

Mouse

试剂准备

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.

复溶

Urano-Tashiro, Y., et al. Infect. Immun. 76(10):4686-4691(2008) Mambole, A., et al. J. Biol. Chem. 283(35):23627-23635(2008) Seethala, R.R., et al. Appl. Immunohistochem. Mol. Morphol. 16(2):165-172(2008) Khunkaewla, P., et al. Mol. Immunol. 45(6):1703-1711(2008) Rawal, A., et al. Arch. Pathol. Lab. Med. 131(11):1673-1678(2007)

储存条件

Human

储存溶液

Leukosialin, Galactoglycoprotein, GALGP, Leukocyte sialoglycoprotein, Sialophorin, CD43, SPN, CD43

应用

WB~~1:100~250

产品描述

Function One of the major glycoproteins of thymocytes and T lymphocytes. Plays a role in the physicochemical properties of the T-cell surface and in lectin binding. Presents carbohydrate ligands to selectins. Has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. Is a counter-receptor for SN/Siglec-1 (By similarity). During T-cell activation is actively removed from the T-cell-APC (antigen-presenting cell) contact site thus suggesting a negative regulatory role in adaptive immune response (By similarity). Cellular_Location Membrane; Single-pass type I membrane protein Tissue_Location Cell surface of thymocytes, T-lymphocytes, neutrophils, plasma cells and myelomas

数量

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