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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > 单克隆抗体 > SLINGSHOT-1L Antibody

SLINGSHOT-1L Antibody

LM21016
货号 货期 规格 / 价格 询价

SLINGSHOT-1L Antibody

品牌

Leading Biology

货号

LM21016

产品分类

单克隆抗体

研究领域

产品概述

Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

纯度

Mouse

复溶

Molecules. 2012 Dec 17;17(12):14975-94.Nan Fang Yi Ke Da Xue Xue Bao. 2011 Jun;31(6):928-32.

储存条件

Human

储存溶液

Protein phosphatase Slingshot homolog 1, 3.1.3.16, 3.1.3.48, SSH-like protein 1, SSH-1L, hSSH-1L, SSH1, KIAA1298, SSH1L

应用

E~~1/10000 IF~~1/200 - 1/1000 FC~~1/200 - 1/400

产品描述

Function Protein phosphatase which regulates actin filament dynamics. Dephosphorylates and activates the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Inhibitory phosphorylation of cofilin is mediated by LIMK1, which may also be dephosphorylated and inactivated by this protein. Cellular_Location Cytoplasm, cytoskeleton. Cell projection, lamellipodium. Cleavage furrow. Midbody. Note=Also recruited to actin rich membrane protrusions such as lamellipodia, which may allow local control of actin dynamics at sites of cell locomotion Also localized to the cleavage furrow and the midbody during cytokinesis

数量

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