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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > 单克隆抗体 > SH3BP2 Antibody (monoclonal) (M01)

SH3BP2 Antibody (monoclonal) (M01)

LM21001
货号 货期 规格 / 价格 询价

SH3BP2 Antibody (monoclonal) (M01)

品牌

Leading Biology

货号

LM21001

产品分类

单克隆抗体

研究领域

产品概述

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

形式

The protein encoded by this gene has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases , and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism. Multiple transcript variants encoding different isoforms have been found for this gene.

浓度

SH3BP2 (AAH22996, 452 a.a. ~ 561 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

纯度

mouse

试剂准备

Clear, colorless solution in phosphate buffered saline, pH 7.2.

复溶

Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.New genetic associations detected in a host response study to hepatitis B vaccine. Davila S, et al. Genes Immun, 2010 Apr. PMID 20237496.NFATc1 and TNFalpha expression in giant cell lesions of the jaws. Amaral FR, et al. J Oral Pathol Med, 2010 Mar. PMID 20002873.Tyrosine phosphorylation of 3BP2 regulates B cell receptor-mediated activation of NFAT. Shukla U, et al. J Biol Chem, 2009 Dec 4. PMID 19833725.Novel mutations in the SH3BP2 gene associated with sporadic central giant cell lesions and cherubism. Carvalho VM, et al. Oral Dis, 2009 Jan. PMID 19017279.

储存条件

Human

储存溶液

SH3 domain-binding protein 2, 3BP-2, SH3BP2, 3BP2

应用

WB~~1:500~1000

数量

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