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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > 单克隆抗体 > SCAP1 Antibody (monoclonal) (M01)

SCAP1 Antibody (monoclonal) (M01)

LM20979
货号 货期 规格 / 价格 询价

SCAP1 Antibody (monoclonal) (M01)

品牌

Leading Biology

货号

LM20979

产品分类

单克隆抗体

研究领域

产品概述

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

形式

This gene encodes a T cell adaptor protein, a class of intracellular molecules with modular domains capable of recruiting additional proteins but that exhibit no intrinsic enzymatic activity. The encoded protein contains a unique N-terminal region followed by a PH domain and C-terminal SH3 domain. Along with the adhesion and degranulation-promoting adaptor protein, the encoded protein plays a critical role in inside-out signaling by coupling T-cell antigen receptor stimulation to the activation of integrins.

浓度

SCAP1 (AAH47870, 1 a.a. ~ 358 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

纯度

mouse

试剂准备

Clear, colorless solution in phosphate buffered saline, pH 7.2.

复溶

Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.T cell receptor inside-out pathway via signaling module SKAP1-RapL regulates T cell motility and interactions in lymph nodes. Raab M, et al. Immunity, 2010 Apr 23. PMID 20346707.A novel S3S-TAP-tag for the isolation of T-cell interaction partners of adhesion and degranulation promoting adaptor protein. Lehmann R, et al. Proteomics, 2009 Dec. PMID 19798671.SKAP associates with kinetochores and promotes the metaphase-to-anaphase transition. Fang L, et al. Cell Cycle, 2009 Sep 1. PMID 19667759.SKAP55 modulates T cell antigen receptor-induced activation of the Ras-Erk-AP1 pathway by binding RasGRP1. Kosco KA, et al. Mol Immunol, 2008 Jan. PMID 17658605.

储存条件

Human

储存溶液

Src kinase-associated phosphoprotein 1, Src family-associated phosphoprotein 1, Src kinase-associated phosphoprotein of 55 kDa, SKAP-55, pp55, SKAP1, SCAP1, SKAP55

应用

WB~~1:500~1000

数量

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