品牌 |
Leading Biology | 货号 |
LM20931 |
产品分类 |
单克隆抗体 | 研究领域 |
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形式 |
Down-regulates signaling from heterotrimeric G-proteins by increasing the GTPase activity of the alpha subunits, thereby driving them into their inactive GDP-bound form. Down-regulates G- protein-mediated release of inositol phosphates and activation of MAP kinases.
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浓度 |
Human RGS3 |
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纯度 |
Mouse |
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复溶 |
Druey K.M.,et al.Nature 379:742-746(1996).
Kehrl J.H.,et al.Genomics 79:860-868(2002).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Chatterjee T.K.,et al.Submitted (DEC-2001) to the EMBL/GenBank/DDBJ databases.
Puhl H.L. III,et al.Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases.
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储存条件 |
Human
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储存溶液 |
Regulator of G-protein signaling 3, RGP3, RGS3, RGS3
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应用 |
IF (10 μg/ml), IHC-P (5 μg/ml),
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产品描述 |
Function
Down-regulates signaling from heterotrimeric G-proteins by increasing the GTPase activity of the alpha subunits, thereby driving them into their inactive GDP-bound form. Down-regulates G- protein-mediated release of inositol phosphates and activation of MAP kinases.
Cellular_Location
Cytoplasm. Nucleus. Cell membrane; Peripheral membrane protein Note=Long isoforms are cytoplasmic and associated with the plasma membrane. Short isoforms are nuclear
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数量 |
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