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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > 单克隆抗体 > RAPGEF1 Antibody (monoclonal) (M01)

RAPGEF1 Antibody (monoclonal) (M01)

LM20913
货号 货期 规格 / 价格 询价

RAPGEF1 Antibody (monoclonal) (M01)

品牌

Leading Biology

货号

LM20913

产品分类

单克隆抗体

研究领域

产品概述

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

形式

This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined.

浓度

RAPGEF1 (AAH41710, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

纯度

mouse

试剂准备

Clear, colorless solution in phosphate buffered saline, pH 7.2.

复溶

1.The WAVE2 complex regulates T cell receptor signaling to integrins via Abl- and CrkL-C3G-mediated activation of Rap1.Nolz JC, Nacusi LP, Segovis CM, Medeiros RB, Mitchell JS, Shimizu Y, Billadeau DD.J Cell Biol. 2008 Sep 22;182(6):1231-44.

储存条件

Human

储存溶液

Rap guanine nucleotide exchange factor 1, CRK SH3-binding GNRP, Guanine nucleotide-releasing factor 2, Protein C3G, RAPGEF1, GRF2

应用

WB~~1:500~1000

数量

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