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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > 单克隆抗体 > NEU2 Antibody (monoclonal) (M02)

NEU2 Antibody (monoclonal) (M02)

LM20710
货号 货期 规格 / 价格 询价

NEU2 Antibody (monoclonal) (M02)

品牌

Leading Biology

货号

LM20710

产品分类

单克隆抗体

研究领域

产品概述

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

形式

This gene belongs to a family of glycohydrolytic enzymes which remove sialic acid residues from glycoproteins and glycolipids. Expression studies in COS7 cells confirmed that this gene encodes a functional sialidase. Its cytosolic localization was demonstrated by cell fractionation experiments.

浓度

NEU2 (NP_005374, 180 a.a. ~ 268 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

纯度

mouse

试剂准备

Clear, colorless solution in phosphate buffered saline, pH 7.2.

复溶

Defective myogenic differentiation of human rhabdomyosarcoma cells is characterized by sialidase Neu2 loss of expression. Stoppani E, et al. Cell Biol Int, 2009 Sep. PMID 19524683.A nonsynonymous SNP in human cytosolic sialidase in a small Asian population results in reduced enzyme activity: potential link with severe adverse reactions to oseltamivir. Li CY, et al. Cell Res, 2007 Apr. PMID 17426694.Crystal structure of the human cytosolic sialidase Neu2. Evidence for the dynamic nature of substrate recognition. Chavas LM, et al. J Biol Chem, 2005 Jan 7. PMID 15501818.The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.Neu4, a novel human lysosomal lumen sialidase, confers normal phenotype to sialidosis and galactosialidosis cells. Seyrantepe V, et al. J Biol Chem, 2004 Aug 27. PMID 15213228.

储存条件

Human

储存溶液

Sialidase-2, Cytosolic sialidase, N-acetyl-alpha-neuraminidase 2, NEU2

数量

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