全部产品分类
品牌 |
Leading Biology | 货号 |
LM20677 |
产品分类 |
单克隆抗体 | 研究领域 |
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产品概述 |
Store at 2 to 8°C.Antibody is stable for 24 months.
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形式 |
Recognizes 78kDa moesin protein. Moesin, a member of the talin-4.1 superfamily, is a linking protein of the submembraneous actin cytoskeleton. It is expressed in variable amounts in cells of different phenotypes such as macrophages, lymphocytes, fibroblastic, endothelial, epithelial, and neuronal cell lines but not in blood cells. The ERM proteins, ezrin, radixin, and moesin are involved in a variety of cellular functions, such as cell adhesion, migration, and the organization of cell surface structures, and are highly homologous, both in protein sequence and in functional activity, with merlin/schwannomin, a neurofibromatosis-2-associated tumor-suppressor protein. Cell lines of epithelial and mesothelial origin contain both moesin and radixin whereas cells of endothelial and lymphoid origin express moesin.
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浓度 |
Recombinant human Moesin protein |
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纯度 |
Mouse |
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试剂准备 |
0.5 ml at 200ug/ml with BSA and azide
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复溶 |
1. Lankes W et. al., Biochem Journal, 1988; 251:831-842.
2. Schwartz-Albiez R et. al., European Journal Cell Biology, 1995; 67:189-198.
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储存条件 |
Human
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储存溶液 |
Moesin, Membrane-organizing extension spike protein, MSN
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产品描述 |
Function
Probably involved in connections of major cytoskeletal structures to the plasma membrane. May inhibit herpes simplex virus 1 infection at an early stage.
Cellular_Location
Cell membrane; Peripheral membrane protein; Cytoplasmic side Cytoplasm, cytoskeleton. Apical cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, microvillus membrane; Peripheral membrane protein; Cytoplasmic side. Note=Phosphorylated form is enriched in microvilli-like structures at apical membrane (By similarity). Increased cell membrane localization of both phosphorylated and non-phosphorylated forms seen after thrombin treatment. {ECO:0000250, ECO:0000269|PubMed:18586956}
Tissue_Location
In all tissues and cultured cells studied.
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数量 |
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| 选择 | 品牌 | 货号 | 产品名称 | 规格 | 分类 | 研究领域 | 说明书 | 数量 | 目录价 | |
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| 4 | Swant | 345 | Monoclonal antibody to rat pyramidal cells. | 200 µl | 单克隆抗体 | Miscellaneous antibodies |
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| 6 | Swant | 77 | mouse monoclonal antibody against rat angiotensinogen | 200 µl | 单克隆抗体 | Antibodies against components of the renin-angiotensin system |
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