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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > 单克隆抗体 > MAPK6 Antibody (monoclonal) (M02)

MAPK6 Antibody (monoclonal) (M02)

LM20638
货号 货期 规格 / 价格 询价

MAPK6 Antibody (monoclonal) (M02)

品牌

Leading Biology

货号

LM20638

产品分类

单克隆抗体

研究领域

产品概述

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

形式

The protein encoded by this gene is a member of the Ser/Thr protein kinase family, and is most closely related to mitogen-activated protein kinases (MAP kinases). MAP kinases also known as extracellular signal-regulated kinases (ERKs), are activated through protein phosphorylation cascades and act as integration points for multiple biochemical signals. This kinase is localized in the nucleus, and has been reported to be activated in fibroblasts upon treatment with serum or phorbol esters.

浓度

MAPK6 (AAH35492, 612 a.a. ~ 721 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

纯度

mouse

试剂准备

Clear, colorless solution in phosphate buffered saline, pH 7.2.

复溶

Activation loop phosphorylation of the atypical MAP kinases ERK3 and ERK4 is required for binding, activation and cytoplasmic relocalization of MK5. D?l?ris P, et al. J Cell Physiol, 2008 Dec. PMID 18720373.Regulation of ERK3/MAPK6 expression by BRAF. Hoeflich KP, et al. Int J Oncol, 2006 Oct. PMID 16964379.Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Kimura K, et al. Genome Res, 2006 Jan. PMID 16344560.The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.N-Terminal ubiquitination of extracellular signal-regulated kinase 3 and p21 directs their degradation by the proteasome. Coulombe P, et al. Mol Cell Biol, 2004 Jul. PMID 15226418.

储存条件

Human, Mouse, Rat

储存溶液

Mitogen-activated protein kinase 6, MAP kinase 6, MAPK 6, Extracellular signal-regulated kinase 3, ERK-3, MAP kinase isoform p97, p97-MAPK, MAPK6, ERK3, PRKM6

应用

WB~~1:500~1000

数量

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