品牌 |
Leading Biology | 货号 |
LM20632 |
产品分类 |
单克隆抗体 | 研究领域 |
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产品概述 |
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
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形式 |
This gene encodes a member of the serine/threonine proteinkinase family. This kinase contains a leucine-zipper domain and ispredominately expressed in neuronal cells. The phosphorylationstate of this kinase in synaptic terminals was shown to beregulated by membrane depolarization via calcineurin. This kinaseforms heterodimers with leucine zipper containing transcriptionfactors, such as cAMP responsive element binding protein (CREB) andMYC, and thus may play a regulatory role in PKA or retinoic acidinduced neuronal differentiation. Alternatively spliced transcriptvariants encoding different proteins have been described.[providedby RefSeq].
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浓度 |
This MAP3K12 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 828-859 amino acids from human MAP3K12. |
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纯度 |
Mouse |
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试剂准备 |
Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
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复溶 |
Clague, J., et al. Mol. Carcinog. 49(2):183-189(2010)
Robitaille, H., et al. J. Invest. Dermatol. 130(1):74-85(2010)
Landa, I., et al. PLoS Genet. 5 (9), E1000637 (2009) :
Daviau, A., et al. Cell. Signal. 21(4):577-587(2009)
Mukhopadhyay, R., et al. Mol. Cell 32(3):371-382(2008)
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储存条件 |
Human, Mouse
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储存溶液 |
Mitogen-activated protein kinase kinase kinase 12, Dual leucine zipper bearing kinase, DLK, Leucine-zipper protein kinase, ZPK, MAPK-upstream kinase, MUK, Mixed lineage kinase, MAP3K12, ZPK
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应用 |
WB~~1:800
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产品描述 |
Function
May be an activator of the JNK/SAPK pathway. Phosphorylates beta-casein, histone 1 and myelin basic protein in vitro.
Cellular_Location
Cytoplasm. Membrane; Peripheral membrane protein
Tissue_Location
Highly expressed in brain and kidney.
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数量 |
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| 选择 | 品牌 | 货号 | 产品名称 | 规格 | 分类 | 研究领域 | 说明书 | 数量 | 目录价 | |
| 1 | Swant | 2D7 | monoclonal anti-Glutamate antibody | 200 µl | 单克隆抗体 | Antibodies against neurotransmitters |
|
¥5096.00 | 订购 询价 | |
| 2 | Leading Biology | LM21248 | Anti-CD36 Antibody (Rabbit Monoclonal antibody) | 100 ul | 单克隆抗体 | Chondrogenesis Markers |
|
¥4950.00 | 订购 询价 | |
| 3 | Swant | 288 | Monoclonal antibody to endothelial cells. | 单克隆抗体 |
|
¥3243.00 | 订购 询价 | |||
| 4 | Swant | 345 | Monoclonal antibody to rat pyramidal cells. | 200 µl | 单克隆抗体 | Miscellaneous antibodies |
|
¥3243.00 | 订购 询价 | |
| 5 | Swant | 3A12 | monoclonal anti-GABA antibody | 200 µl | 单克隆抗体 | Antibodies against neurotransmitters |
|
¥5096.00 | 订购 询价 | |
| 6 | Swant | 77 | mouse monoclonal antibody against rat angiotensinogen | 200 µl | 单克隆抗体 | Antibodies against components of the renin-angiotensin system |
|
¥4015.00 | 订购 询价 |
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