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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > 单克隆抗体 > MAP3K12 Antibody (Ascites)

MAP3K12 Antibody (Ascites)

LM20632
货号 货期 规格 / 价格 询价

MAP3K12 Antibody (Ascites)

品牌

Leading Biology

货号

LM20632

产品分类

单克隆抗体

研究领域

产品概述

Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

形式

This gene encodes a member of the serine/threonine proteinkinase family. This kinase contains a leucine-zipper domain and ispredominately expressed in neuronal cells. The phosphorylationstate of this kinase in synaptic terminals was shown to beregulated by membrane depolarization via calcineurin. This kinaseforms heterodimers with leucine zipper containing transcriptionfactors, such as cAMP responsive element binding protein (CREB) andMYC, and thus may play a regulatory role in PKA or retinoic acidinduced neuronal differentiation. Alternatively spliced transcriptvariants encoding different proteins have been described.[providedby RefSeq].

浓度

This MAP3K12 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 828-859 amino acids from human MAP3K12.

纯度

Mouse

试剂准备

Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

复溶

Clague, J., et al. Mol. Carcinog. 49(2):183-189(2010) Robitaille, H., et al. J. Invest. Dermatol. 130(1):74-85(2010) Landa, I., et al. PLoS Genet. 5 (9), E1000637 (2009) : Daviau, A., et al. Cell. Signal. 21(4):577-587(2009) Mukhopadhyay, R., et al. Mol. Cell 32(3):371-382(2008)

储存条件

Human, Mouse

储存溶液

Mitogen-activated protein kinase kinase kinase 12, Dual leucine zipper bearing kinase, DLK, Leucine-zipper protein kinase, ZPK, MAPK-upstream kinase, MUK, Mixed lineage kinase, MAP3K12, ZPK

应用

WB~~1:800

产品描述

Function May be an activator of the JNK/SAPK pathway. Phosphorylates beta-casein, histone 1 and myelin basic protein in vitro. Cellular_Location Cytoplasm. Membrane; Peripheral membrane protein Tissue_Location Highly expressed in brain and kidney.

数量

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