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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > 单克隆抗体 > KPNA1 Antibody (monoclonal) (M01)

KPNA1 Antibody (monoclonal) (M01)

LM20538
货号 货期 规格 / 价格 询价

KPNA1 Antibody (monoclonal) (M01)

品牌

Leading Biology

货号

LM20538

产品分类

单克隆抗体

研究领域

产品概述

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

形式

Recombination activating proteins RAG1 and RAG2 regulate and mediate V(D)J recombination, the process by which genes for immunoglobulins and T-cell receptors are generated. Several other ubiquitously expressed proteins are thought to be recruited in the recombination process. Among these are the genes affected in severe combined immune deficiency and genes involved in ds-DNA break repair. The protein encoded by this gene interacts with RAG1 and may play a role in V(D)J recombination. Two transcript variants, one protein-coding and the other not, have been found for this gene.

浓度

KPNA1 (AAH02374.1, 1 a.a. ~ 538 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

纯度

mouse

试剂准备

Clear, colorless solution in phosphate buffered saline, pH 7.2.

复溶

1.Targeted disruption of one of the importin ? family members leads to female functional incompetence in delivery.Moriyama T, Nagai M, Oka M, Ikawa M, Okabe M, Yoneda Y.FEBS J. 2011 Mar 3. doi: 10.1111/ j.1742-4658. 2011.08079.x. [Epub ahead of print]2.Nuclear import impairment causes cytoplasmic trans-activation response DNA-binding protein accumulation and is associated with frontotemporal lobar degeneration.Nishimura AL, Zupunski V, Troakes C, Kathe C, Fratta P, Howell M, Gallo JM, Hortobagyi T, Shaw CE, Rogelj B.Brain. 2010 Jun;133(Pt 6):1763-71. Epub 2010 May 14.

储存条件

Human

储存溶液

Importin subunit alpha-5, Karyopherin subunit alpha-1, Nucleoprotein interactor 1, NPI-1, RAG cohort protein 2, SRP1-beta, Importin subunit alpha-5, N-terminally processed, KPNA1, RCH2

应用

WB~~1:500~1000

数量

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