全部产品分类
品牌 |
Leading Biology | 货号 |
LM20530 |
产品分类 |
单克隆抗体 | 研究领域 |
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产品概述 |
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
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形式 |
KID (KNSL4; kinesin-like DNA-binding protein) is a member of the kinesin family that is involved in spindle formation and the movements of chromosomes during mitosis and meiosis (1). KID colocalizes with mitotic chromosomes and is enriched in the kinetochore at anaphase. The N-terminal region of KID shares greater than 35% sequence homology with the motor domains of other kinesins. The C-terminal domain has limited but significant homology to NOD, a Drosophila protein and member of the kinesin family. KID also contains a putative nuclear localization signal (2). It was demonstrated that SIAH, a human homologue of the Drosophila seven in absentia (Sina), is involved in the degradation of KID via the ubiquitin-proteasome pathway (3). It was also reported that KID function is regulated by phosphorylation. Ser427 and Thr463 were identified as M phase-specific phosphorylation sites (4).
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浓度 |
A phospho-specific peptide corresponding to residues surrounding Serine 427 of human KID was used as an immunogen. This antibody only detects KID phosphorylated on Serine 427. |
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纯度 |
Rabbit |
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试剂准备 |
50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
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复溶 |
1. Song J, et al. Genomics 52(3):374-7, 1998<br>2. Tokai N, et al. EMBO J. 15(3):457-67. 1996<br>3. Germani A, et al. Oncogene 19(52):5997-6006, 2000<br>4. Tokai-Nishizumi N, et al. The EMBO Journal 22: 2091-2103, 2003<br>
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储存条件 |
Human
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储存溶液 |
Kinesin-like protein KIF22, Kinesin-like DNA-binding protein, Kinesin-like protein 4, KIF22, KID, KNSL4
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应用 |
WB~~1:1000~2000
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产品描述 |
Function
Kinesin family that is involved in spindle formation and the movements of chromosomes during mitosis and meiosis. Binds to microtubules and to DNA.
Cellular_Location
Nucleus. Cytoplasm, cytoskeleton
Tissue_Location
Expressed in bone, cartilage, joint capsule, ligament, skin, and primary cultured chondrocytes
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数量 |
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| 选择 | 品牌 | 货号 | 产品名称 | 规格 | 分类 | 研究领域 | 说明书 | 数量 | 目录价 | |
| 1 | Swant | 2D7 | monoclonal anti-Glutamate antibody | 200 µl | 单克隆抗体 | Antibodies against neurotransmitters |
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￥5096.00 | 订购 询价 | |
| 2 | Leading Biology | LM21248 | Anti-CD36 Antibody (Rabbit Monoclonal antibody) | 100 ul | 单克隆抗体 | Chondrogenesis Markers |
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￥4950.00 | 订购 询价 | |
| 3 | Swant | 288 | Monoclonal antibody to endothelial cells. | 单克隆抗体 |
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￥3243.00 | 订购 询价 | |||
| 4 | Swant | 345 | Monoclonal antibody to rat pyramidal cells. | 200 µl | 单克隆抗体 | Miscellaneous antibodies |
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￥3243.00 | 订购 询价 | |
| 5 | Swant | 3A12 | monoclonal anti-GABA antibody | 200 µl | 单克隆抗体 | Antibodies against neurotransmitters |
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￥5096.00 | 订购 询价 | |
| 6 | Swant | 3D5 | monoclonal anti-GABA antibody | 200 µl | 单克隆抗体 | Antibodies against neurotransmitters |
|
￥5096.00 | 订购 询价 |
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