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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > 单克隆抗体 > ITGB2 / CD18 Antibody (clone MEM-48)

ITGB2 / CD18 Antibody (clone MEM-48)

LM20514
货号 货期 规格 / 价格 询价

ITGB2 / CD18 Antibody (clone MEM-48)

品牌

Leading Biology

货号

LM20514

产品分类

单克隆抗体

研究领域

形式

Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrins alpha-M/beta-2 and alpha-X/beta-2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin alpha-X/beta-2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin alpha-M/beta-2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin alpha-M/beta-2 is also a receptor for factor X. Integrin alpha- D/beta-2 is a receptor for ICAM3 and VCAM1. Triggers neutrophil transmigration during lung injury through PTK2B/PYK2-mediated activation.

浓度

Leukocytes of a patient suffering from a LGL-type leukemia

纯度

Mouse

复溶

Kishimoto T.K.,et al.Cell 48:681-690(1987). Weitzman J.B.,et al.FEBS Lett. 294:97-103(1991). Ota T.,et al.Nat. Genet. 36:40-45(2004). Suzuki Y.,et al.Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases. Hattori M.,et al.Nature 405:311-319(2000).

储存条件

Human

储存溶液

Integrin beta-2, Cell surface adhesion glycoproteins LFA-1/CR3/p150, 95 subunit beta, Complement receptor C3 subunit beta, CD18, ITGB2, CD18, MFI7

应用

Flo (2 μg/ml), IHC-P (10 μg/ml), IP (2 μg/ml), WB (2 μg/ml) ,

产品描述

Function Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrins alpha-M/beta-2 and alpha-X/beta-2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin alpha-X/beta-2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin alpha-M/beta-2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin alpha-M/beta-2 is also a receptor for factor X. Integrin alpha- D/beta-2 is a receptor for ICAM3 and VCAM1. Triggers neutrophil transmigration during lung injury through PTK2B/PYK2-mediated activation. Cellular_Location Membrane; Single-pass type I membrane protein

数量

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