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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > 单克隆抗体 > ITGAX/CD11c Antibody (N-term)

ITGAX/CD11c Antibody (N-term)

LM20505
货号 货期 规格 / 价格 询价

ITGAX/CD11c Antibody (N-term)

品牌

Leading Biology

货号

LM20505

产品分类

单克隆抗体

研究领域

产品概述

Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

形式

This gene encodes the integrin alpha X chain protein.Integrins are heterodimeric integral membrane proteins composed ofan alpha chain and a beta chain. This protein combines with thebeta 2 chain (ITGB2) to form a leukocyte-specific integrin referredto as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2complex seems to overlap the properties of the alpha M beta 2integrin in the adherence of neutrophils and monocytes tostimulated endothelium cells, and in the phagocytosis of complementcoated particles.

浓度

This ITGAX/CD11c antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 246-274 amino acids from the N-terminal region of human ITGAX/CD11c.

纯度

Mouse

试剂准备

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.

复溶

Van Brussel, I., et al. J. Immunol. Methods 362 (1-2), 168-175 (2010) : Chen, X., et al. Proc. Natl. Acad. Sci. U.S.A. 107(33):14727-14732(2010) Lindsay, R.W., et al. J. Immunol. 185(3):1513-1521(2010) Kraus, T.S., et al. Am. J. Clin. Pathol. 134(2):271-277(2010) Quist, S.R., et al. Acta Derm. Venereol. 90(4):429-430(2010)

储存条件

Human

储存溶液

Integrin alpha-X, CD11 antigen-like family member C, Leu M5, Leukocyte adhesion glycoprotein p150, 95 alpha chain, Leukocyte adhesion receptor p150, CD11c, ITGAX, CD11C

应用

WB~~1:100~500

产品描述

Function Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis. Cellular_Location Membrane; Single-pass type I membrane protein Tissue_Location Predominantly expressed in monocytes and granulocytes

数量

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