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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > 单克隆抗体 > ITGA4 Antibody

ITGA4 Antibody

LM20501
货号 货期 规格 / 价格 询价

ITGA4 Antibody

品牌

Leading Biology

货号

LM20501

产品分类

单克隆抗体

研究领域

产品概述

Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

纯度

Mouse

复溶

Clin Immunol. 2009 Jun;131(3):472-80. Am J Med Genet B Neuropsychiatr Genet. 2009 Dec 5;150B(8):1147-51.

储存条件

Human

储存溶液

Integrin alpha-4, CD49 antigen-like family member D, Integrin alpha-IV, VLA-4 subunit alpha, CD49d, ITGA4, CD49D

应用

E~~1/10000 WB~~1/500 - 1/2000 FC~~1/200 - 1/400

产品描述

Function Integrins alpha-4/beta-1 (VLA-4) and alpha-4/beta-7 are receptors for fibronectin. They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1. Integrin alpha- 4/beta-1 recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha- 4/beta-7 is also a receptor for MADCAM1. It recognizes the sequence L-D-T in MADCAM1. On activated endothelial cells integrin VLA-4 triggers homotypic aggregation for most VLA-4-positive leukocyte cell lines. It may also participate in cytolytic T-cell interactions with target cells. Cellular_Location Membrane; Single-pass type I membrane protein

数量

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