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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > 单克隆抗体 > HIPK1 Antibody (monoclonal) (M07)

HIPK1 Antibody (monoclonal) (M07)

LM20439
货号 货期 规格 / 价格 询价

HIPK1 Antibody (monoclonal) (M07)

品牌

Leading Biology

货号

LM20439

产品分类

单克隆抗体

研究领域

产品概述

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

形式

The protein encoded by this gene belongs to the Ser/Thr family of protein kinases and HIPK subfamily. It phosphorylates homeodomain transcription factors and may also function as a co-repressor for homeodomain transcription factors. Alternative splicing results in four transcript variants encoding four distinct isoforms.

浓度

HIPK1 (AAH28408, 330 a.a. ~ 430 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

纯度

mouse

试剂准备

Clear, colorless solution in phosphate buffered saline, pH 7.2.

复溶

HIPK1 interacts with c-Myb and modulates its activity through phosphorylation. Matre V, et al. Biochem Biophys Res Commun, 2009 Oct 9. PMID 19646965.Toward a confocal subcellular atlas of the human proteome. Barbe L, et al. Mol Cell Proteomics, 2008 Mar. PMID 18029348.Roles of HIPK1 and HIPK2 in AML1- and p300-dependent transcription, hematopoiesis and blood vessel formation. Aikawa Y, et al. EMBO J, 2006 Sep 6. PMID 16917507.Tumor necrosis factor alpha-induced desumoylation and cytoplasmic translocation of homeodomain-interacting protein kinase 1 are critical for apoptosis signal-regulating kinase 1-JNK/p38 activation. Li X, et al. J Biol Chem, 2005 Apr 15. PMID 15701637.The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.

储存条件

Human

储存溶液

Homeodomain-interacting protein kinase 1, Nuclear body-associated kinase 2, HIPK1, KIAA0630, MYAK, NBAK2

应用

WB~~1:500~1000

数量

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