全部产品分类
品牌 |
Leading Biology | 货号 |
LM20399 |
产品分类 |
单克隆抗体 | 研究领域 |
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产品概述 |
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
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形式 |
Golgi Matrix Protein (GM130) is peripheral cytoplamic protein that is bound to the Golgi membranes. It has been implicated as a maintainer of cis-Golgi structure (1). During mitosis, it regulates the disassembly and reassembly of the Golgi complex. It is also linked to docking and fusion of coatomer (COP I) coated vesicles to the Golgi membrane (2). The COOH-terminal domain of GM130 is highly homologous to Golgi human auto-antigen, golgin-95. GM130 interacts specifically and GTP-dependent manner with Rab1b protein, a regulator of anterograde traffic between ER and Golgi membranes (3). GM130 is also activator of YSK1, an essential player in cell migration.
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浓度 |
A synthetic peptide corresponding to residues near the N-term of human Golgi Matrix Protein (GM130) was used as a immunogen. |
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纯度 |
Rabbit |
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试剂准备 |
50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
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复溶 |
1. Nakamura N, et al. J Cell Biol 131:1715-1726, 1995<br>2. Warren G, Annual Rev Biochem 62:323-348, 1993<br>3. Weide T, et al. EMBO Rep 2:336-341, 2001<br>
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储存条件 |
Human
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储存溶液 |
Golgin subfamily A member 2, 130 kDa cis-Golgi matrix protein, GM130, GM130 autoantigen, Golgin-95, GOLGA2
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应用 |
WB~~1:50000~100000
IHC~~1:250~500
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产品描述 |
Function
Golgi auto-antigen; probably involved in maintaining cis-Golgi structure.
Cellular_Location
Golgi apparatus, Golgi stack membrane; Peripheral membrane protein
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数量 |
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