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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > 单克隆抗体 > FLNA / Filamin A Antibody (clone 4E10-1B2)

FLNA / Filamin A Antibody (clone 4E10-1B2)

LM20354
货号 货期 规格 / 价格 询价

FLNA / Filamin A Antibody (clone 4E10-1B2)

品牌

Leading Biology

货号

LM20354

产品分类

单克隆抗体

研究领域

形式

Promotes orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplasmic signaling proteins. Interaction with FLNA may allow neuroblast migration from the ventricular zone into the cortical plate. Tethers cell surface- localized furin, modulates its rate of internalization and directs its intracellular trafficking (By similarity). Involved in ciliogenesis.

浓度

Human FLNA

纯度

Mouse

复溶

Gorlin J.B.,et al.J. Cell Biol. 111:1089-1105(1990). Patrosso M.C.,et al.Genomics 21:71-76(1994). Chen E.Y.,et al.Hum. Mol. Genet. 5:659-668(1996). Li J.,et al.Mol. Cell. Proteomics 9:2517-2528(2010). Ota T.,et al.Nat. Genet. 36:40-45(2004).

储存条件

Human

储存溶液

Filamin-A, FLN-A, Actin-binding protein 280, ABP-280, Alpha-filamin, Endothelial actin-binding protein, Filamin-1, Non-muscle filamin, FLNA, FLN, FLN1

应用

IHC-P (5 μg/ml), WB (1:500-1:1000),

产品描述

Function Promotes orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplasmic signaling proteins. Interaction with FLNA may allow neuroblast migration from the ventricular zone into the cortical plate. Tethers cell surface- localized furin, modulates its rate of internalization and directs its intracellular trafficking (By similarity). Involved in ciliogenesis. Cellular_Location Cytoplasm, cell cortex. Cytoplasm, cytoskeleton Tissue_Location Ubiquitous.

数量

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