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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > 单克隆抗体 > FKBP5 Antibody (monoclonal) (M02)

FKBP5 Antibody (monoclonal) (M02)

LM20351
货号 货期 规格 / 价格 询价

FKBP5 Antibody (monoclonal) (M02)

品牌

Leading Biology

货号

LM20351

产品分类

单克隆抗体

研究领域

产品概述

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

形式

The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.

浓度

FKBP5 (AAH42605, 1 a.a. ~ 457 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

纯度

mouse

试剂准备

Clear, colorless solution in phosphate buffered saline, pH 7.2.

复溶

Correlation of major depressive disorder symptoms with FKBP5 but not FKBP4 expression in human immunodeficiency virus-infected individuals. Tatro ET, et al. J Neurovirol, 2010 Aug 20. PMID 20726698.Meta-analysis of FKBP5 gene polymorphisms association with treatment response in patients with mood disorders. Zou YF, et al. Neurosci Lett, 2010 Oct 22. PMID 20709156.FKBP5 and resistant attachment predict cortisol reactivity in infants: Gene-environment interaction. Luijk MP, et al. Psychoneuroendocrinology, 2010 May 21. PMID 20547006.Comprehensive copy number variant (CNV) analysis of neuronal pathways genes in psychiatric disorders identifies rare variants within patients. Saus E, et al. J Psychiatr Res, 2010 Apr 14. PMID 20398908.Interaction of FKBP5 with childhood adversity on risk for post-traumatic stress disorder. Xie P, et al. Neuropsychopharmacology, 2010 Jul. PMID 20393453.

储存条件

Human

储存溶液

Peptidyl-prolyl cis-trans isomerase FKBP5, PPIase FKBP5, 51 kDa FK506-binding protein, 51 kDa FKBP, FKBP-51, 54 kDa progesterone receptor-associated immunophilin, Androgen-regulated protein 6, FF1 antigen, FK506-binding protein 5, FKBP-5, FKBP54, p54, HSP90-binding immunophilin, Rotamase, FKBP5, AIG6, FKBP51

应用

WB~~1:500~1000

数量

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