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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > 单克隆抗体 > EhpB6 Antibody

EhpB6 Antibody

LM20291
货号 货期 规格 / 价格 询价

EhpB6 Antibody

品牌

Leading Biology

货号

LM20291

产品分类

单克隆抗体

研究领域

产品概述

Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

纯度

Mouse

复溶

1. J Clin Invest. 2002 Oct;110(8):1141-50. 2. J Biol Chem. 2002 Feb 8;277(6):3823-8. Epub 2001 Nov 16. 3. J Biol Chem. 2003 Mar 21;278(12):10150-6. Epub 2003 Jan 6. 4. Biochem Biophys Res Commun. 2006 Feb 3;340(1):268-76.

储存条件

Human

储存溶液

Ephrin type-B receptor 6, HEP, Tyrosine-protein kinase-defective receptor EPH-6, EPHB6

应用

WB~~1/500 - 1/2000 IHC~~1/200 - 1/1000

产品描述

Function Kinase-defective receptor for members of the ephrin-B family. Binds to ephrin-B1 and ephrin-B2. Modulates cell adhesion and migration by exerting both positive and negative effects upon stimulation with ephrin-B2. Inhibits JNK activation, T-cell receptor-induced IL-2 secretion and CD25 expression upon stimulation with ephrin-B2. Cellular_Location Membrane; Single-pass type I membrane protein Tissue_Location Expressed in brain. Expressed in non invasive breast carcinoma cell lines (at protein level). Strong expression in brain and pancreas, and weak expression in other tissues, such as heart, placenta, lung, liver, skeletal muscle and kidney Expressed in breast non invasive tumors but not in metastatic lesions. Isoform 3 is expressed in cell lines of glioblastomas, anaplastic astrocytomas, gliosarcomas and astrocytomas. Isoform 3 is not detected in normal tissues.

数量

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